Welcome to the Keto Battalion, home of Battle Brew’s Elite Ketone fueled troops. This battalion is comprised of Battle Brew troops who follow MCT accelerated Ketogenic diets.
Ketosis is a metabolic state where most of the body’s energy supply comes from Ketone bodies in the blood, in contrast to a state of glycolysis where blood glucose provides most of the energy. Ketone bodies are formed by Ketogenesis which occurs when liver glycogen stores are depleted.
In the case of MCTs, their rapid absorption and transport to the liver results in Ketone production regardless of whether the glycogen stores are depleted or not which is why MCTs may help to protect your muscles after exercise.
The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon.
Ketosis is characterised by serum concentrations of ketone bodies over 0.5 millimolar with low and stable levels of insulin and blood glucose. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.
Ketosis which is not harmful or dangerous should not be confused with Ketoacidosis which can be a life threatening condition.
People with normally functioning bodies should never produce dangerous build ups of ketones in their systems because of the regulatory effect of insulin. Type 1 diabetics however do not produce enough insulin and can be at risk of developing Ketoacidosis which is why they should be very careful on Ketogenic diets or when taking MCTs which can rapidly elevate ketone levels in the blood.
In the case of a normally functioning body, in nutritional Ketosis, the concentration of Ketone bodies in the blood do not exceed 3.0 millimolar but this may rise to 3.5 millimolar after exercising. For your body to go into Ketoacidosis you would need to have concentrations of Ketone bodies ranging from 15-25 millimolar which should never occur unless you are a type 1 diabetic.
The presence of Ketones can be tested with a urine test stick or a blood tester. Urine measurements may not reflect blood concentrations and urine concentrations will be lower with greater hydration. After adaptation to a Ketogenic diet the amount lost in the urine drops while the metabolism remains Ketotic. In addition most urine strips only measure acetoacetate, while after adaptation the predominant Ketone body is β-hydroxybutyrate.
During the usual overnight fast the body’s metabolism naturally switches into Ketosis, and will normally switch back to glycolysis after a carbohydrate-rich meal. Longer-term Ketosis may result from intermittent fasting or staying on a low-carbohydrate diet, and deliberately induced Ketosis serves as a medical intervention for epilepsy and a number of other conditions. In glycolysis higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in Ketosis fat reserves are readily released and consumed. This is the reason Ketosis is sometimes referred to as the body’s “fat burning” mode
One of the best resources we have found for explaining Ketosis and a Ketogenic diet is Keto Clarity by Jimmy Moore with Eric Westman, MD.
We would highly recommend that anyone considering, or on, a Ketogenic diet reads this book.
Jimmy’s rather busy but informative blog can be found here
A Guide to Ketosis by Joseph Arcita
Ketogenic Diet Resources by Ellen Davis
A Beginners Guide to the Keto Diet – by rule.me
Articles and Science
Ketogenic diets and physical performance by Stephen D Phinney
Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals – Kathy Musa-Veloso, Sergei S Likhodii, and Stephen C Cunnane
Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet – Likhodii SS, Musa K, Cunnane SC.